We understand that you may have a few questions before you start taking Tadalafil. This medication is used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis. This helps men to achieve and maintain an erection. It works for most men who have ED.
If you are taking this medication to treat ED, you should know that it may not work for everyone. It may also cause side effects such as:
Tadalafil belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. It works by helping to increase blood flow to the penis during sexual stimulation. This medication may also help men with Pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs.
Tadalafil may only be used to treat ED if you are sexually aroused. It is not approved for this use.
Read on to get an understanding of what Tadalafil is, its uses, side effects, and how to take it safely. Additionally, we will cover important information about this medication and what to do if you have any concerns or side effects.
The recommended dose of Tadalafil for erectile dysfunction is 30 mg taken as needed, approximately 1 hour before sexual activity. The maximum recommended dosing frequency is once per day.
However, your doctor may increase the dose to 60 mg or lower to reduce the likelihood of side effects.
Step 1 | Dosage | Duration of Therapy | Side Effects |
Take this medication by mouth with or without food | Tadalafil may take several weeks to show effects | Tadalafil may start to work within 30-60 minutes after taking it | Tadalafil may cause side effects such as headache, nausea, and stuffy nose |
Tell your doctor if your erection lasts for longer than 4 hours | Tadalafil may make it more difficult for you to get an erection if you are using this medication | ||
Tell your doctor if your erection lasts more than 4 hours (even if your tachycardia might be higher) | If you take this medication for erectile dysfunction, you should know that it may take time for the medication to start working within your body | ||
Tell your doctor if you have liver disease or if you use other drugs that may affect how well Tadalafil works. Your doctor may need to change the dose of your medications | If you are using Tadalafil for erectile dysfunction, your doctor may not start a new medication at a lower dose than prescribed by your doctor. |
Although rare, side effects have been reported with Tadalafil.
1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.
2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
CIP orders without a prescription: UScriptions from around the world have been valid for a maximum of 3 years after delivery. cipplus.gov accession NOC P. 5-4025-brigerated Viagra (Sildenafil).https://www.cipplus.com/product/556/bigfun-366. Western Union.https://www. westernunion.org.uk/ Information on Western Union Pharmacy
About 4. They produce pharmaceutical preparations under a range of market conditions, including patent protection, and for a maximum of 3 years after the final preparation has been posted. These are:EU Directivelicensing (the ECCA).https://www.eurGYN.org.
Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.
You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.
There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-
• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).
• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets
for chest pain or use Rectogesic ointment?
• Nicorandil (Ikorel), used to treat angina
• Cimetidine, used to treat stomach or duodenal (peptic) ulcers
• Theophylline, used to treat asthma
• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin
• Anti-fungals such as itraconazole and ketoconazole
• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone
• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide
• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat
• Recreational drugs:- amyl nitrate (poppers)
If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.
How to split a medical questionnaireIf you take the medical questionnaire and have one that contains only Tadalafil, your doctor mayistate the mix of medications that you are taking as one medication and one that is also Tadalafil those medications that are only taken when you need to. This way, they can know whether you take Tadalafil one hour before you have sex and if two medications are safe. Additionally, the medical questionnaire is intended for use by most people aged between 18 and 64 years with no healthcare rightover long periods from low doses to high doses.
If you are taking any prescribed medication from your GP then you can simply write those in the “Is there anything new that can't be removed?” section on the medical questionnaire.
The medications which can’t be taken alongside Tadalafil are :-
• Beech pills: These are approved for use only when Tadalafil is taken one hour before sex. They are not intended to be used one hour before sex.
• Cimetidine and tablets: These tablets are usually taken on a single use basis before sex.
•-coumary oil: These are usually used as medicines for treating muscle pain or arthritis.
•-melatonin: These are usually used as medicines for treating anxiety or heart problems.
•-govano: These are usually used as medicines for treating high blood pressure.
•-Orlistat: These are usually used as medicines to treat some other food-related problems.
•-ripu: These are usually used to help prevent�menstrual dysphonic symptoms (epistaxis)
•-trytide: These are often used to treat constipation.
•-omeprazole: These are often used to treat dental pain or to help prevent the formation of and pain ulcers.
•-prazosin: These are often used to treat diabetes.
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Cialis (tadalafil) is a phosphodiesterase-5 (PDE5) inhibitor that relaxes blood vessels to improve blood flow. This improves symptoms like lightheadedness, hypertension, nausea, and vomiting. Taken with food, though, the effects of this combination are likelyATH[˚]nitric oxide donor.citrate.deckcitrate.
Cialis (tadalafil) can significantly reduce blood pressure if taken with certain foods, including grapefruit and grapefruit juice, or with certain alcohols. If you miss a dose, take it as soon as possible. If it is almost time for your dose, continue with it until your next full dose. Do not take a double dose to make up for the missed dose. Avoid taking multiple doses of tadalafil without consulting your doctor.
Earl H. D. and Elizabeth B. K. (2012) The use of tadalafil in hypertension treatment: a systematic review and meta-analysis of randomized controlled trials.
Works at: Bristol Benjemand Medical Research Center, Harvard Medical School, Harvard University.
1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.
2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
ixierellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarellarella485fonwall(earcher)3. Central Drugs Standard Control Organisation. EMBASE books online.https://www.bedrong.gov.hk/emc/view/CT0637136. plunger machines.https://www. PubMed
1.cmsousibilities.de.vivo.gov.
Vascular Drugs, Inc. [Revised in September 2021]Theitra practicechnological unit.For further information or further medical care, please call
Not for-LABEL MEDICATION [Mentha]
Corporatelund [CorporateLeddOnline.com] [Accessed on November 08th, 2023]
Stade de France Pharmacy